with lithium no need to do that at all, i have all kinds of lithium for these tests and for electric vehicles and DIY flashlights amps etc... No matter how you use them they will not have any weird effects like the old crappy NiCD/NiHM battery's, only 2 things to keep in mind: Don't go under 2V (ill say 2.5V to be safe) and don't go over 4.23V then all is good.